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Heterogeneous Nuclear Ribonucleoprotein D-Like (HNRPDL) (Middle Region) Peptid

HNRPDL Reaktivität: Human Wirt: Synthetic BP, WB
Produktnummer ABIN5673564

Kurzübersicht für Heterogeneous Nuclear Ribonucleoprotein D-Like (HNRPDL) (Middle Region) Peptid (ABIN5673564)

Target

HNRPDL (Heterogeneous Nuclear Ribonucleoprotein D-Like (HNRPDL))

Spezies

Human

Quelle

  • 9
Synthetic

Applikation

Blocking Peptide (BP), Western Blotting (WB)
  • Protein Region

    Middle Region

    Sequenz

    GRGAAAGGRG GTRGRGRGQG QNWNQGFNNY YDQGYGNYNS AYGGDQNYSG

    Produktmerkmale

    This is a synthetic peptide designed for use in combination with anti- HNRPDL Antibody. It may block above mentioned antibody from binding to its target protein in western blot and/or immunohistochecmistry under proper experimental settings. There is no guarantee for its use in other applications.
  • Applikationshinweise

    Optimal working dilution should be determined by the investigator.

    Beschränkungen

    Nur für Forschungszwecke einsetzbar
  • Format

    Lyophilized

    Rekonstitution

    Add 100 μL of sterile PBS. Final peptide concentration is 1 mg/mL in PBS.

    Lagerung

    -20 °C

    Informationen zur Lagerung

    For longer periods of storage, store at -20°C. Avoid repeat freeze-thaw cycles.
  • Target

    HNRPDL (Heterogeneous Nuclear Ribonucleoprotein D-Like (HNRPDL))

    Hintergrund

    This gene belongs to the subfamily of ubiquitously expressed heterogeneous nuclear ribonucleoproteins (hnRNPs). The hnRNPs are RNA binding proteins and they complex with heterogeneous nuclear RNA (hnRNA). These proteins are associated with pre-mRNAs in the nucleus and appear to influence pre-mRNA processing and other aspects of mRNA metabolism and transport. While all of the hnRNPs are present in the nucleus, some seem to shuttle between the nucleus and the cytoplasm. The hnRNP proteins have distinct nucleic acid binding properties. The protein encoded by this gene has two RRM domains that bind to RNAs. Three alternatively spliced transcript variants have been described for this gene. One of the variants is probably not translated because the transcript is a candidate for nonsense-mediated mRNA decay. The protein isoforms encoded by this gene are similar to its family member HNRPD.

    Alias Symbols: HNRNP, JKTBP, HNRPDL, JKTBP2, LGMD1G, laAUF1

    Protein Size: 301

    Gen-ID

    9987

    NCBI Accession

    NM_001207000, NP_001193929
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